Litcius/Paper detail

Resistance to Poly (ADP-Ribose) Polymerase Inhibitors (PARPi): Mechanisms and Potential to Reverse

Christina Washington, Kathleen N. Moore

2022Current Oncology Reports15 citationsDOI

Topics & Concepts

MedicinePolymeraseSynthetic lethalityCancer researchAcquired resistancePoly ADP ribose polymeraseMutationCancerDNA repairGeneticsInternal medicineBiologyDNAGenePARP inhibition in cancer therapyOvarian cancer diagnosis and treatmentToxin Mechanisms and Immunotoxins