Low-Dose Perampanel Rescues Cortical Gamma Dysregulation Associated With Parvalbumin Interneuron GluA2 Upregulation in Epileptic Syngap1+/− Mice
Brennan J. Sullivan, Simon G. Ammanuel, Pavel A. Kipnis, Yoichi Araki, Richard L. Huganir, Shilpa D. Kadam
Topics & Concepts
PerampanelAMPA receptorParvalbuminHaploinsufficiencyNeuroscienceEpilepsyIctalInterneuronEpileptogenesisPsychologyMedicineInternal medicineBiologyGlutamate receptorPhenotypeReceptorGeneticsInhibitory postsynaptic potentialGeneNeuroscience and Neuropharmacology ResearchEpilepsy research and treatmentGenetics and Neurodevelopmental Disorders