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Percutaneous Pulmonary Flow Restriction in Infants With Congenital Heart Disease

Matthew D. Warren, Ana Vasquez Choy, Mohammed Q. Khan, Matthew Brown, Damien J. LaPar, Jorge D. Salazar, Kiran K. Mallula

2024JACC Advances10 citationsDOIOpen Access PDF

Abstract

Background: Restriction of PBF in infants born with CHD is often required to avoid pulmonary over-circulation prior to definitive intervention. The current standard is to surgically place pulmonary artery bands, but these have limitations and are associated with complications. Objectives: The purpose of this study was to a single-center experience with a relatively novel technique to percutaneously restrict pulmonary blood flow (PBF) in select infants with congenital heart disease (CHD). Methods: Patients were selected to undergo this procedure either due to low birth weight or prematurity. All of them had CHD that would result in over-circulation without control of PBF. By a percutaneous method, modified vascular plug devices were placed in the bilateral branch pulmonary arteries. Results: and a mean transpulmonary gradient of 5.9 mm Hg. Conclusions: Percutaneous PBF restriction appears to be safe and a less invasive option to delay surgical intervention in a select population to allow for somatic growth and gestational maturation. It results in a decrease in the total number of sternotomies.

Topics & Concepts

PercutaneousCardiologyMedicineHeart diseaseInternal medicineCongenital Heart Disease StudiesCongenital Diaphragmatic Hernia StudiesNeonatal Respiratory Health Research