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Educational attainment does not influence brain aging

Lars Nyberg, Fredrik Magnussen, Anders Lundquist, William F.C. Baaré, David Bartrés‐Faz, Lars Bertram, Carl‐Johan Boraxbekk, Andreas M. Brandmaier, Christian A. Drevon, Klaus P. Ebmeier, Paolo Ghisletta, Richard N. Henson, Carme Junqué, Rogier Kievit, Maike Kleemeyer, Ethan Knights, Simone Kühn, Ulman Lindenberger, Brenda W.J.H. Penninx, Sara Pudas, Øystein Sørensen, Lídia Vaqué‐Alcázar, Kristine B. Walhovd, Anders M. Fjell

2021Proceedings of the National Academy of Sciences103 citationsDOIOpen Access PDF

Abstract

Education has been related to various advantageous lifetime outcomes. Here, using longitudinal structural MRI data (4,422 observations), we tested the influential hypothesis that higher education translates into slower rates of brain aging. Cross-sectionally, education was modestly associated with regional cortical volume. However, despite marked mean atrophy in the cortex and hippocampus, education did not influence rates of change. The results were replicated across two independent samples. Our findings challenge the view that higher education slows brain aging.

Topics & Concepts

Brain agingBrain sizeHippocampusPsychologyEducational attainmentAtrophyCortex (anatomy)NeuroscienceAging brainLongitudinal studyGerontologyDevelopmental psychologyCognitionMedicineInternal medicineMagnetic resonance imagingPolitical sciencePathologyLawRadiologyFunctional Brain Connectivity StudiesAdvanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research
Educational attainment does not influence brain aging | Litcius