Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
Geoffrey M. Lynn, Christine Sedlik, Faezzah Baharom, Yaling Zhu, Ramiro A. Ramirez-Valdez, Vincent Coble, Kennedy K.S. Tobin, Sarah R. Nichols, Yaakov Itzkowitz, Neeha Zaidi, Joshua M. Gammon, Nicolas J. Blobel, Jordan Denizeau, Philippe De La Rochère, Brian J. Francica, Brennan Decker, Mateusz Maciejewski, Justin Cheung, Hidehiro Yamane, Margery Smelkinson, Joseph R. Francica, Richard Laga, Joshua D. Bernstock, Leonard W. Seymour, Charles G. Drake, Christopher M. Jewell, Olivier Lantz, Eliane Piaggio, Andrew S. Ishizuka, Robert A. Seder
Topics & Concepts
ConjugateAntigenPeptideImmunityCD8Cross-presentationVirologyChemistryCell biologyBiologyImmune systemImmunologyBiochemistryMHC class IMathematicsMathematical analysisImmunotherapy and Immune ResponsesAntimicrobial Peptides and Activitiesvaccines and immunoinformatics approaches