Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
Iman Halvaei, Julia F. Litzky, Navid Esfandiari
Abstract
Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.
Topics & Concepts
OffspringReproductionPostponementSpermDemographyLife expectancyAssisted reproductive technologyFertilityReproductive healthBiologyMedicineInfertilityAndrologyPregnancyPopulationGeneticsSociologyBusinessMarketingAssisted Reproductive Technology and Twin PregnancyReproductive Health and TechnologiesDemographic Trends and Gender Preferences