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Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics

Hirohito Yamaguchi, Jung-Mao Hsu, Wenhao Yang, Mien‐Chie Hung

2022Nature Reviews Clinical Oncology474 citationsDOI

Topics & Concepts

MedicineSmall moleculeImmune checkpointCancer researchComputational biologyDownregulation and upregulationPD-L1CancerAcetylationImmune systemTranslational researchBioinformaticsImmunotherapyBiologyImmunologyInternal medicineGeneGeneticsPathologyCancer Immunotherapy and BiomarkersPeptidase Inhibition and AnalysisLung Cancer Research Studies
Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics | Litcius