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Biological agents for severe asthma: the evolution of the at-home self-injection approach

Carlo Lombardi, Diego Bagnasco, Giovanni Passalacqua

2020Current Opinion in Allergy and Clinical Immunology19 citationsDOI

Abstract

PURPOSE OF REVIEW: New biological agents, in addition to the well-established omalizumab, have been nowadays introduced into clinical practice for severe asthma. This suggested the possibility of an at-home self-administration, as currently happening for other biological agents for immune-mediated diseases. RECENT FINDINGS: In the very recent years, there were structured clinical trials investigating the self at home administrations of biologicals for severe asthma, showing with different principles, a possible advantage and convenience for the patient, and a socioeconomic saving. SUMMARY: The literature analysis currently shows that the at-home self-administration of biologicals for severe asthma is a promising approach to improve the treatment of such disease.

Topics & Concepts

MedicineOmalizumabAsthmaIntensive care medicineClinical trialDiseaseImmunologyInternal medicineImmunoglobulin EAntibodyAsthma and respiratory diseasesPediatric health and respiratory diseasesInhalation and Respiratory Drug Delivery