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PIONEER: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis (SM) With Symptoms Inadequately Controlled by Standard Therapy

Cem Akin, Hanneke Oude Elberink, Jason Gotlib, Vito Sabato, Karin Hartmann, Sigurd Broesby‐Olsen, Mariana Castells, Michael W. Deininger, Mark Heaney, Tracy I. George, Deepti Radia, Massimo Triggiani, Paul Van Daele, Daniel J. DeAngelo, Oleg Schmidt-Kittler, Huimin Lin, A. Morrison, Brenton G. Mar, Frank Sibenhaar, Marcus Maurer

2020Journal of Allergy and Clinical Immunology18 citationsDOI

Topics & Concepts

MedicineTryptaseSystemic mastocytosisPlaceboInternal medicineAdverse effectGastroenterologyNauseaMast cellBone marrowImmunologyPathologyAlternative medicineMast cells and histamineImmunodeficiency and Autoimmune DisordersAsthma and respiratory diseases