PIONEER: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis (SM) With Symptoms Inadequately Controlled by Standard Therapy
Cem Akin, Hanneke Oude Elberink, Jason Gotlib, Vito Sabato, Karin Hartmann, Sigurd Broesby‐Olsen, Mariana Castells, Michael W. Deininger, Mark Heaney, Tracy I. George, Deepti Radia, Massimo Triggiani, Paul Van Daele, Daniel J. DeAngelo, Oleg Schmidt-Kittler, Huimin Lin, A. Morrison, Brenton G. Mar, Frank Sibenhaar, Marcus Maurer
Topics & Concepts
MedicineTryptaseSystemic mastocytosisPlaceboInternal medicineAdverse effectGastroenterologyNauseaMast cellBone marrowImmunologyPathologyAlternative medicineMast cells and histamineImmunodeficiency and Autoimmune DisordersAsthma and respiratory diseases