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Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole

Tatsuki Asai, Naruhiko Adachi, Toshio Moriya, Hideyuki Oki, Takamitsu Maru, Masato Kawasaki, K. Suzuki, Si-Si Chen, Ryohei Ishii, Kazuko Yonemori, S. Igaki, Satoshi Yasuda, Satoshi Ogasawara, Toshiya Senda, Takeshi Murata

2021Structure95 citationsDOI

Topics & Concepts

hERGAstemizolePotassium channelPotassium channel blockerChemistryPharmacologyBiophysicsRepolarizationElectrophysiologyInternal medicineMedicineBiologyForce Microscopy Techniques and ApplicationsCardiac electrophysiology and arrhythmiasIntegrated Circuits and Semiconductor Failure Analysis
Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole | Litcius