Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration
Oscar Fraile‐Μartinez, Cielo García‐Montero, Alejandro Coca, Miguel Ángel Álvarez-Mon, Jorge Monserrat, Ana M. Gómez-Lahoz, Santiago Coca, Melchor Álvarez‐Mon, Julio Acero, Julia Buján, Natalio García‐Honduvilla, Ángel Asúnsolo, Miguel Á. Ortega
Abstract
Polymer-based composites are a group of biomaterials that exert synergic and combined activity. There are multiple reported uses of these composites in multiple biomedical areas, such as drug carriers, in wound dressings, and, more prominently, in tissue engineering and regenerative medicine. Bone grafting is a promising field in the use of polymeric composites, as this is the second most frequently transplanted organ in the United States. Advances in novel biomaterials, such as polymeric composites, will undoubtedly be of great aid in bone tissue engineering and regeneration. In this paper, a general view of bone structure and polymeric composites will be given, discussing the potential role of these components in bone tissue. Moreover, the most relevant jawbone and maxillofacial applications of polymeric composites will be revised in this article, collecting the main knowledge about this topic and emphasizing the need of further clinical studies in humans.