Litcius/Paper detail

Association Between Admission Blood Fibrinogen-To-Albumin Ratio and Clinical Outcomes After Acute Lacunar Stroke

Lukai Zheng, Zhetao Wang, Junfeng Liu, Xue Yang, Shihong Zhang, Zilong Hao, Ming Liu, Deren Wang

2021Biomarkers in Medicine18 citationsDOI

Abstract

Aim: We aimed to investigate the influence of admission fibrinogen-to-albumin ratio (FAR) on 3-month outcomes after acute lacunar stroke. Materials & methods: Consecutive patients with acute lacunar stroke were included and classified into two groups according to an optimized FAR cut-off value determined by receiver operating characteristic curve analysis. Results: Compared with those with low FAR (<0.077), patients from the high FAR group (≥0.077) had significantly higher risk for 3-month disability and the composite outcome of death/disability. After logistic regression adjustment, high FAR was still significantly associated with 3-month disability and death/disability. Conclusion: FAR ≥0.077 on admission might be an independent predictor of disability and death/disability at 3 months after lacunar stroke, which needs to be verified in future studies.

Topics & Concepts

MedicineLacunar strokeLogistic regressionFibrinogenInternal medicineStroke (engine)Receiver operating characteristicCardiologyPhysical therapyIschemic strokeIschemiaMechanical engineeringEngineeringAcute Ischemic Stroke ManagementBlood properties and coagulationVenous Thromboembolism Diagnosis and Management