TROPHY-U-01, a phase II open-label study of sacituzumab govitecan in patients with metastatic urothelial carcinoma progressing after platinum-based chemotherapy and checkpoint inhibitors: updated safety and efficacy outcomes
Yohann Loriot, Daniel P. Petrylak, Arash Rezazadeh Kalebasty, Aude Fléchon, Rohit Jain, Sumati Gupta, Manojkumar Bupathi, Philippe Beuzeboc, Phillip L. Palmbos, Arjun Vasant Balar, Christos E. Kyriakopoulos, Damien Pouessel, Cora N. Sternberg, Julia Tonelli, M. Sierecki, Hao Zhou, Petros Grivas, Philippe Barthélémy, Scott T. Tagawa
Topics & Concepts
MedicineIrinotecanInternal medicineOncologyClinical endpointAdverse effectProgression-free survivalSorafenibChemotherapyCancerSurgeryGastroenterologyColorectal cancerClinical trialHepatocellular carcinomaBladder and Urothelial Cancer TreatmentsPeptidase Inhibition and AnalysisCancer therapeutics and mechanisms