Litcius/Paper detail

Phenyl-quinoline derivatives as lead structure of cholinesterase inhibitors with potency to reduce the GSK-3β level targeting Alzheimer's disease

Milad Noori, Navid Dastyafteh, Sajedeh Safapoor, Minoo Khalili Ghomi, Romina Tanideh, Kamiar Zomorodian, Haleh Hamedifar, Mahintaj Dara, Shahrokh Zare, Cambyz Irajie, Shahrzad Javanshir, Hossein Rastegar, Nikoo Panahi, Bagher Larijani, Mohammad Mahdavi, Mir Hamed Hajimiri, Aida Iraji

2023International Journal of Biological Macromolecules24 citationsDOI

Topics & Concepts

ButyrylcholinesteraseQuinolineChemistryAcetylcholinesteraseCholinesteraseSubstituentPotencyAchéStereochemistryEnzymeIn vitroPharmacologyBiochemistryOrganic chemistryMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsEnzyme function and inhibition