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Recent Advances in Pediatric Cancer Research

Troy A. McEachron, Lee J. Helman

2021Cancer Research24 citationsDOIOpen Access PDF

Abstract

Over the past few years, the field of pediatric cancer has experienced a shift in momentum, and this has led to new and exciting findings that have relevance beyond pediatric malignancies. Here we present the current status of key aspects of pediatric cancer research. We have focused on genetic and epigenetic drivers of disease, cellular origins of different pediatric cancers, disease models, the tumor microenvironment, and cellular immunotherapies.

Topics & Concepts

Pediatric cancerMedicineCancerDiseasePediatric oncologyEpigeneticsIntensive care medicinePediatric researchBlood cancerOncologyMEDLINERelevance (law)BioinformaticsChildhood cancerNeuroblastoma Research and TreatmentsAcute Lymphoblastic Leukemia researchRenal and related cancers