Chemotherapy de-escalation using an 18F-FDG-PET-based pathological response-adapted strategy in patients with HER2-positive early breast cancer (PHERGain): a multicentre, randomised, open-label, non-comparative, phase 2 trial
José Manuel Pérez-García, Géraldine Gebhart, Manuel Ruíz Borrego, Agostina Stradella, Begoña Bermejo, Peter Schmid, Frederik Marmé, Santiago Escrivá-de-Romaní, Lourdes Calvo, Nuria Ribelles, Noelia Martínez-Jáñez, Cinta Albacar, Aleix Prat, Florence Dalenc, Khaldoun Kerrou, Marco Colleoni, N. Afonso, Serena Di Cosimo, Miguel Sampayo-Cordero, Andrea Malfettone, Javier Cortés, Antonio Llombart‐Cussac
Topics & Concepts
PertuzumabMedicineBreast cancerTrastuzumabInternal medicineLetrozoleDocetaxelTamoxifenCarboplatinOncologyClinical endpointRandomized controlled trialChemotherapyCancerCisplatinBreast Cancer Treatment StudiesHER2/EGFR in Cancer ResearchAdvanced Breast Cancer Therapies