Spleen-selective co-delivery of mRNA and TLR4 agonist-loaded LNPs for synergistic immunostimulation and Th1 immune responses
Longze Pan, Lijing Zhang, Wenjing Deng, Jia Lou, Xiaoke Gao, Xiaohan Lou, Yangyang Liu, Xiaohan Yao, Yuqiao Sheng, Yan Yan, Ni Chen, Ming Wang, Chuntao Tian, Fazhan Wang, Zhihai Qin
Topics & Concepts
Immune systemSpleenAntigenImmunologyCytotoxic T cellOvalbuminImmunotherapyBiologyCancer researchIn vitroBiochemistryRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesVirus-based gene therapy research