The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress
Terytty Yang Li, Maroun Bou Sleiman, Hao Li, Arwen W. Gao, Adrienne Mottis, Alexis Bachmann, Gaby El Alam, Xiaoxu Li, Ludger J.E. Goeminne, Kristina Schoonjans, Johan Auwerx
Topics & Concepts
BiologyCaenorhabditis elegansP300-CBP Transcription FactorsCoactivatorCell biologyLongevityTranscription factorGeneticsMitochondrionGeneHistone AcetyltransferasesGenetics, Aging, and Longevity in Model OrganismsGenomics, phytochemicals, and oxidative stressEndoplasmic Reticulum Stress and Disease