Litcius/Paper detail

Is the bell-shaped dose-response curve of the selective serotonin reuptake inhibitor due to 5-HT1A auto-receptors?

Takeshi Terao, Nobuyoshi Ishii, Hirofumi Hirakawa, Eiji Aoshima

2020Medical Hypotheses20 citationsDOI

Topics & Concepts

Serotonin reuptake inhibitorSerotoninPharmacologyArea under the curveReuptake inhibitorReceptorDose dependenceDose–response relationshipTherapeutic windowMedicineInternal medicineNeurotransmitter Receptor Influence on BehaviorTreatment of Major DepressionReceptor Mechanisms and Signaling