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Recent Advances to Mediate Reductive Processes of Nitroarenes Using Single-Electron Transfer, Organomagnesium, or Organozinc Reagents

Tom G. Driver, Haoran Zhu

2022Synthesis32 citationsDOIOpen Access PDF

Abstract

Abstract Nitroarenes are readily available compounds that are commonly utilized in reductive processes to form C–NAr bonds via reactive nitrogen intermediates. Recent advances in the development of reductive reactions of nitroarenes using organomagnesium, organozinc, and single-electron transfer reagents are discussed within this short review. 1 Introduction 2 Organomagnesium-Mediated Reductive Reactions of Nitroarenes 3 Organozinc- and Zinc-Mediated Reductive Reactions of Nitroarenes 4 Iodine-Catalyzed Redox Cyclizations of Nitroarenes 5 Titanium(III)-Mediated Reductive Cyclizations 6 Sulfur-Mediated Reductive Reactions of Nitroarenes 7 Alkoxide-Mediated Reductive Reactions of Nitroarenes 8 4,4′-Bipyridine-Mediated Reductive Reactions of Nitroarenes 9 Visible-Light-Driven Reductive Amination Reactions 10 Electrochemical Reductive Reactions 11 Conclusion

Topics & Concepts

ChemistryReductive eliminationReductive aminationReagentRedoxElectron transferAlkoxideCombinatorial chemistryOrganic chemistryCatalysisNanomaterials for catalytic reactionsChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods