Litcius/Paper detail

The novel dual-mechanism Kv7 potassium channel/TSPO receptor activator GRT-X is more effective than the Kv7 channel opener retigabine in the 6-Hz refractory seizure mouse model

Petra Bloms‐Funke, Marion Bankstahl, Jens P. Bankstahl, Christa Kneip, Wolfgang Schröder, Wolfgang Löscher

2021Neuropharmacology16 citationsDOI

Topics & Concepts

PharmacologyEpilepsyPotassium channelNeuroprotectionChemistryNeuroactive steroidTranslocator proteinAllosteric regulationAnxiolyticAnticonvulsantSeizure thresholdMedicineNeurosciencePsychologyInternal medicineReceptorGABAA receptorInflammationNeuroinflammationIon channel regulation and functionNeuroscience and Neuropharmacology ResearchCardiac electrophysiology and arrhythmias
The novel dual-mechanism Kv7 potassium channel/TSPO receptor activator GRT-X is more effective than the Kv7 channel opener retigabine in the 6-Hz refractory seizure mouse model | Litcius