The NLRP3 inflammasome: Mechanism of action, role in disease and therapies
Li Wang, Arthur V. Hauenstein
Topics & Concepts
InflammasomePyroptosisProinflammatory cytokineInflammationProgrammed cell deathMechanism (biology)Cell biologyCaspase 1Signal transductionPattern recognition receptorReceptorCytosolBiologyChemistryImmunologyApoptosisEnzymeInnate immune systemBiochemistryEpistemologyPhilosophyInflammasome and immune disordersKawasaki Disease and Coronary ComplicationsHeme Oxygenase-1 and Carbon Monoxide