Highlights from the 1st European cancer dependency map symposium and workshop
Lucia Trastulla, Aurora Savino, Pedro Beltrão, Isidro Cortés‐Ciriano, Peter Fenici, Mathew J. Garnett, Ilaria Guerini, Núria López Bigas, Iain W. Mattaj, Evangelia Petsalaki, Laura Riva, Christopher J. Tape, Jolanda van Leeuwen, Sumana Sharma, Francisca Vázquez, Francesco Iorio
Abstract
The systematic identification of tumour vulnerabilities through perturbational experiments on cancer models, including genome editing and drug screens, is playing a crucial role in combating cancer. This collective effort is known as the Cancer Dependency Map (DepMap). The 1st European Cancer Dependency Map Symposium (EuroDepMap), held in Milan last May, featured talks, a roundtable discussion, and a poster session, showcasing the latest discoveries and future challenges related to the DepMap. The symposium aimed to facilitate interactions among participants across Europe, encourage idea exchange with leading experts, and present their work and future projects. Importantly, it sparked discussions on future endeavours, such as screening more complex cancer models and accounting for tumour evolution.