ОЦЕНКА ЭФФЕКТИВНОСТИ КОНСЕРВАТИВНОГО МЕТОДА ЛЕЧЕНИЯ РАННЕЙ СТАДИИ ДИАБЕТИЧЕСКОЙ РЕТИНОПАТИИ

Abstract

Relevance. Early detection of lesions and maintenance of the normal functioning of the retinal tissue at an earlystage of non-proliferative diabetic retinopathy (NPDR) is considered an extremely important step in its secondary prevention,which makes it advisable to include angioprotective drugs in the complex of conservative therapy. One of the drugs of interestis «Dobesilate calcium» drug that improves retinal microcirculation, is able to prevent and correct biochemical changes in nervetissues, and has an endothelioprotective effect. The purpose of the study. The aim of the study was to evaluate the effectivenessof the use of the drug «Dobesilate calcium» in patients with an early stage of NPDR. Material and methods. 60 patients (120eyes) were examined, the average age of which was 59.4±6.2 years, of which 52.6% were men, 47.4% were women. Results.Analysis of the results showed that in the group of patients who received «Dobesilate calcium» there was an improvement invisual acuity by an average of 0.20±0.02 (p<0.05), a decrease in the thickness of the retina (CTS) by an average of 1.60 micron(p<0.05), as well as a decrease in the thickness of the retina in other parts of the central zone in 75% of cases (44 eyes). Whilein the control group, the studied functional and Doppler indicators did not change significantly (p>0.05). Conclusion. This studyshowed that the treatment with the drug «Dobesilate calcium» helps to improve eye blood flow in retrobulbar vessels, whichmakes it possible to recommend the specified method of treatment for the secondary prevention of the development of diabeticretinopathy and restorative treatment of patients from the early stages of the NDPR.

Topics & Concepts