Accelerating Drug Development Using Spatial Multi-omics
Richard J. A. Goodwin, Stefan Platz, Jorge S. Reis‐Filho, Simon T. Barry
Abstract
SUMMARY: Spatial biology approaches enabled by innovations in imaging biomarker platforms and artificial intelligence-enabled data integration and analysis provide an assessment of patient and disease heterogeneity at ever-increasing resolution. The utility of spatial biology data in accelerating drug programs, however, requires balancing exploratory discovery investigations against scalable and clinically applicable spatial biomarker analysis.
Topics & Concepts
Computer scienceSpatial analysisBiomarkerDrug developmentScalabilityComputational biologyData scienceDrug discoveryBiomarker discoveryPrecision medicineDrugBioinformaticsBiologyMedicineProteomicsGeographyRemote sensingDatabasePharmacologyPathologyBiochemistryGeneSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsHealth Systems, Economic Evaluations, Quality of Life