Agent-Based Modeling of Epidemics: Approaches, Applications, and Future Directions
Xiangyu Zhang, Jiaojiao Wang, Chunmiao Yu, Jiaqiang Fei, Tianyi Luo, Zhidong Cao
Abstract
The spread of infectious diseases is inherently linked to human social behavior, characterized by complexity, diversity, and openness. Intelligent agents in computer science provide a powerful framework for capturing such dynamics, enabling complex epidemic patterns to emerge from simple local rules. These agents exhibit self-organization, adaptability, and self-optimization, making them well suited for individual-level modeling. Agent-based models (ABMs) have shown promising results in epidemic simulation and policy evaluation. However, current implementations often suffer from simplistic behavioral assumptions and rigid interaction mechanisms, limiting their realism and flexibility. This paper first reviews the current landscape of epidemic modeling approaches. It then analyzes the underlying mechanisms of advanced intelligent agents, highlighting their modeling capabilities. The study focuses on four key advantages of intelligent agent-based modeling and elaborates on three critical roles these agents play in evaluating and optimizing intervention strategies.