A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs
Tatsuya Shimizu, Shin-Ichi Mae, Toshikazu Araoka, Keisuke Okita, Akitsu Hotta, Kunihiro Yamagata, Kenji Osafune
Topics & Concepts
PKD1Autosomal dominant polycystic kidney diseaseInduced pluripotent stem cellOrganoidPolycystic kidney diseaseDiseaseKidneyKidney diseaseBiologyMedicinePathologyBioinformaticsCancer researchGeneInternal medicineGeneticsEmbryonic stem cellGenetic and Kidney Cyst DiseasesRenal and related cancersRenal cell carcinoma treatment