Updated Analysis of the Surface Carbohydrate Gene Clusters in a Diverse Panel of Acinetobacter baumannii Isolates
Johanna J. Kenyon, Ruth M. Hall
Abstract
To enhance the utility of the genetically diverse panel of Acinetobacter baumannii isolates reported recently by Galac and coworkers (M. R. Galac, E. Snesrud, F. Lebreton, J. Stam, et al., Antimicrob Agents Chemother 64:e00840-20, 2020, https://doi.org/10.1128/AAC.00840-20) and to identify the novel KL and OCL, all of the gene clusters that direct the biosynthesis of capsular polysaccharide and of the outer core of lipooligosaccharide, respectively, were reexamined. The nine KL and one OCL previously recorded as novel were identified, and nine further novel KL and two OCL were found.
Topics & Concepts
Acinetobacter baumanniiBiologyGeneMicrobiologyNeisseriaceaeAcinetobacterGene clusterBacteriaGeneticsAntibioticsOpportunistic pathogenBacterial geneticsPolysaccharideStrain (injury)PhylogeneticsBacterial capsuleEnterobacteriaceaeComputational biologyMicrobial Natural Products and BiosynthesisCarbohydrate Chemistry and SynthesisMicrobial Metabolism and Applications