Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist’s perspective
Adrian B.C. Lee, Meng-How Tan, Christina L. L. Chai
Topics & Concepts
CRISPRGenome editingComputational biologyGeneEnhancerCas9Context (archaeology)GenomeSmall moleculeHomology directed repairBiologyDNAGenetic enhancementGeneticsDNA repairNucleotide excision repairGene expressionPaleontologyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery