CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues
Micha L. Davila, Ming Xu, Chenyu Huang, Erin R. Gaddes, Levi Winter, Margherita T. Cantorna, Yong Wang, Na Xiong
Abstract
T cells into lungs and reproductive tracts, the latter of which also exhibit spontaneous inflammation. Our findings demonstrate that CCL27 is critical for immune homeostasis across barrier tissues.
Topics & Concepts
Immune systemBiologyChemokineCell biologyHomeostasisInflammationImmunologyCCL20Knockout mouseChemokine receptorReceptorBiochemistryDermatology and Skin DiseasesPsoriasis: Treatment and PathogenesisT-cell and B-cell Immunology