Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers
Qiong Wu, Yue Song, Ruotong Liu, Rui Wang, Wenjie Mei, Wei‐Ming Chen, Huanglan Yang, Xicheng Wang
Topics & Concepts
ChemistryG-quadruplexDoxorubicinApoptosisDNAStereochemistryImidazoleDocking (animal)Combinatorial chemistryBiochemistryChemotherapyMedicineNursingSurgeryDNA and Nucleic Acid ChemistrySynthesis and Biological EvaluationCancer therapeutics and mechanisms