Phytochemical Profiling in Conjunction with <i>In Vitro</i> and <i>In Silico</i> Studies to Identify Human α-Amylase Inhibitors in <i>Leucaena leucocephala</i> (Lam.) De Wit for the Treatment of Diabetes Mellitus
Renganathan Senthil, Sakthivel Manokaran, Preethi Vasanthakumar, Usha Singaravelu, Pok‐Son Kim, Arne Kutzner, Klaus Heese
Abstract
(Lam.) De Wit-derived hexadecanoic acid and oleic acid are natural product-based antidiabetic compounds that can potentially be used to manage diabetes mellitus.
Topics & Concepts
PhytochemicalAmylaseIn silicoOleic acidChemistryMimosineEnzymeBiochemistryLupeolLeucaena leucocephalaBiologyBotanyGeneNatural Antidiabetic Agents StudiesEnzyme Production and CharacterizationComputational Drug Discovery Methods