Computational-based drug repurposing methods in COVID-19
Yosef Masoudi‐Sobhanzadeh
Abstract
COVID-19, as a newly emerging disease, has disrupted human's different activities. Hence, it is essential to develop drugs or vaccines in order to control COVID-19. Since there is not a medication or vaccine for treating the disease and drug development project is a time and cost consuming process, drug repurposing approaches may yield to proper curing plans. However, there are some limitations in this field, which make the process a challenging one. This letter aims to introduce drug repurposing methods and the existing challenges to detect candidate drugs which may be helpful in controlling COVID-19.
Topics & Concepts
Drug repositioningRepurposingCoronavirus disease 2019 (COVID-19)DrugRisk analysis (engineering)Computer scienceDrug developmentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakDrug discoveryInfectious disease (medical specialty)DiseaseMedicinePharmacologyBioinformaticsEngineeringVirologyBiologyOutbreakPathologyWaste managementComputational Drug Discovery MethodsInnovative Microfluidic and Catalytic Techniques InnovationAdvanced Biosensing Techniques and Applications