Litcius/Paper detail

Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS–MAPK pathway and TP53 as potential predictors of immunotherapy efficacy

Jingyuan Wang, Joanne Xiu, Yasmine Baca, Hiroyuki Arai, Francesca Battaglin, Natsuko Kawanishi, Shivani Soni, W. Zhang, Joshua Millstein, Anthony F. Shields, Axel Grothey, Benjamin A. Weinberg, John L. Marshall, Emil Lou, Moh’d Khushman, Davendra Sohal, Michael J. Hall, Matthew J. Oberley, David Spetzler, Lin Shen, W. Michael Korn, Heinz‐Josef Lenz

2021Annals of Oncology26 citationsDOIOpen Access PDF

Topics & Concepts

Microsatellite instabilityMedicineKRASHazard ratioImmunotherapyCancerCancer researchOncologyInternal medicinePD-L1MAPK/ERK pathwayKinaseConfidence intervalGeneBiologyGeneticsMicrosatelliteColorectal cancerAlleleCancer Immunotherapy and BiomarkersEsophageal Cancer Research and TreatmentFerroptosis and cancer prognosis