KI-Catalyzed Allylic Sulfonation of α-Methylstyrene Derivatives with Sulfonylhydrazides via Electrochemistry
Xinghua Zhang, Shuang Xu, Yang Xiang, Wan Pang
Abstract
A direct allylic C-H bond activation of α-methylstyrene derivatives with sulfonylhydrazines for the synthesis of allylic sulfones has been developed under exogenous oxidant- and metal-catalyst-free electrochemical conditions. Using the transfer of electrons in the current instead of a stoichiometric chemical oxidant, a series of valuable allylic sulfones were accessed with a wide substrate scope and excellent regioselectivity via radical coupling.
Topics & Concepts
Allylic rearrangementCatalysisRegioselectivityElectrochemistryStoichiometryChemistrySubstrate (aquarium)Electron transferCombinatorial chemistryOrganic chemistryElectrodePhysical chemistryGeologyOceanographySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods