Stimulating macropinocytosis of peptide-drug conjugates through DNA-dependent protein kinase inhibition for treating KRAS-mutant cancer
Ha Rin Kim, Seong Jin Park, Young Seok Cho, Mudhibadhi Knowledge Moyo, Jeong Uk Choi, Na Kyeong Lee, Seung Woo Chung, Seho Kweon, Jooho Park, Byoungmo Kim, Yoon Gun Ko, Joo Hye Yeo, Jinu Lee, Sang Yoon Kim, Youngro Byun
Topics & Concepts
KRASMutantCancer cellCancer researchPinocytosisYAP1BiologyCancerChemistryColorectal cancerReceptorBiochemistryGeneTranscription factorGeneticsEndocytosisCancer-related Molecular PathwaysChromatin Remodeling and CancerUbiquitin and proteasome pathways