Alcohol and breast cancer
Beata Starek‐Świechowicz, Bogusława Budziszewska, A Stárek
Abstract
Breast cancer is one of the main causes of death in women worldwide. In women, breast cancer includes over half of all tumours caused by alcohol. This paper discusses both ethanol metabolism and the mechanisms of mammary tumourigenesis caused by alcohol. Numerous signalling pathways in neoplastic transformation following alcohol consumption in women have been presented. In addition, primary and secondary prevention, phytochemicals, synthetic chemicals, specific inhibitors of enzymes and selective receptor modulators have been described.
Topics & Concepts
Breast cancerCancerPharmacotherapyMedicinePharmacyOncologyInternal medicineFamily medicineAlcohol Consumption and Health EffectsCancer, Lipids, and MetabolismMetabolism, Diabetes, and Cancer