In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes
David A. Tess, George Chang, Christopher Keefer, Anthony Carlo, Rhys Jones, Li Di
Topics & Concepts
In vivoMicrosomePharmacologyChemistryComputational biologyIn vitroBiochemistryBiologyBiotechnologyPharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsMetabolomics and Mass Spectrometry Studies