The α-synuclein seed amplification assay: Interpreting a test of Parkinson's pathology
Alberto J. Espay, Andrew Lees, Francisco Cardoso, Steven J. Frucht, Daniel Erskine, Ivette M. Sandoval, Luis Daniel Bernal-Conde, Andrea Sturchio, Alberto Imarisio, Christian Pieter Hoffmann, Kora T Montemagno, Dragomir Milovanović, Glenda M. Halliday, Fredric P. Manfredsson
Topics & Concepts
SeedingNucleationPathogenesisPathologicalAlpha-synucleinPathologyProtein aggregationPrecipitationChemistryCerebrospinal fluidAmyloid (mycology)DiseaseMedicineParkinson's diseaseBiologyBiochemistryOrganic chemistryAgronomyMeteorologyPhysicsParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsNeurological diseases and metabolism