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<scp>WHO</scp> classification of skin tumours: key updates in the fifth edition

Gabrielle Goldman‐Lévy, Raymond L. Barnhill, Boris C. Bastian, Werner Kempf, David E. Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane L. Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony J. Gill, Jennelle C. Hodge, Joseph D. Khoury, Kátia Ramos Moreira Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Zhiyong Liang, Holger Moch, Rajendra Singh, H. D. Wijesinghe, Ian A. Cree, Dilani Lokuhetty

2025Histopathology8 citationsDOIOpen Access PDF

Abstract

The 5th edition of the World Health Organization Classification of Tumours (WCT) serves as a foundation for global diagnostic standards in tumour pathology. Similar to other volumes in this series, the Skin Tumours (Skin5) edition follows a standardized approach. This edition introduces two new chapters: 'Tumours of the nail unit' and 'Metastases to skin', along with new entities across relevant chapters. This review article provides an overview of the updates in Skin5 based on currently published evidence, with emphasis on newly introduced chapters and newly described entities that involve the skin, in particular, epidermal, melanocytic and appendageal tumours.

Topics & Concepts

Key (lock)Computer scienceMedicineFoundation (evidence)Data scienceMEDLINEMedical physicsSkin tumoursInformation retrievalNail (fastener)Nonmelanoma Skin Cancer StudiesCutaneous Melanoma Detection and ManagementCancer and Skin Lesions
<scp>WHO</scp> classification of skin tumours: key updates in the fifth edition | Litcius