NLRP3 Inflammasome Inhibition Prevents α-Synuclein Pathology by Relieving Autophagy Dysfunction in Chronic MPTP–Treated NLRP3 Knockout Mice
Zhou Ou, Yuanzhang Zhou, Lijun Wang, Liujun Xue, Jinlong Zheng, Liam Chen, Qiang Tong
Topics & Concepts
InflammasomeMPTPAutophagyDopaminergicNeuroprotectionKnockout mouseNeuroinflammationParkinson's diseaseDopaminePharmacologyChemistryMedicineBiologyInflammationEndocrinologyPathologyInternal medicineBiochemistryReceptorDiseaseApoptosisParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyRestless Legs Syndrome Research