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Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway

Haohuan Li, Xuezhong Wang, Jianping Li, Xiaoming Yang, Jun Huang, Chuang Ji, Xuyang Li, Li Lan, Jianlin Zhou, Yong Hu

2023Chemico-Biological Interactions21 citationsDOI

Topics & Concepts

ApoptosisOxidative stressProgrammed cell deathViability assayGPX4ChemistryCell biologyCell growthCancer researchBiologyGlutathione peroxidaseBiochemistrySuperoxide dismutaseGinseng Biological Effects and ApplicationsCancer-related molecular mechanisms researchCancer-related Molecular Pathways
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway | Litcius