Rapid Inactivation of SARS-CoV-2 with Ozonated Water
Hiroko Inagaki, Akatsuki Saito, Putu Eka Sudaryatma, Hironobu Sugiyama, Tamaki Okabayashi, Shouichi Fujimoto
Abstract
Although ozonated water is one of the promising candidates for hand hygiene to prevent fomite infection, the detailed effects of ozonated water on SARS-CoV-2 have not been clarified. We evaluated the inactivating effect of ozonated water against SARS-CoV-2 by its concentration and exposure time. The reduction rates of virus titer after 5 sec treatment with ozone concentrations of 1, 4, 7, and 10 mg/L were 81.4%, 93.2%, 96.6%, and 96.6%, respectively. No further decrease in virus titer was observed by the extended exposure time over 5 sec. High-concentration ozonated water, such as more than 7 mg/L, was considered to be effective in promptly inactivating SARS-CoV-2 virus in aqueous solution.