Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents
Jingxuan Chen, Jingxuan Chen, Ling Li, Jin Liu, Sijie Yuan, Wenzhen Liao, Andrzej Słomiński, Wěi Li, Michał A. Żmijewski, Jianjun Chen, Jianjun Chen
Topics & Concepts
ChemistryLipopolysaccharideNitric oxide synthaseNitric oxideProstaglandin E2Downregulation and upregulationColitisPharmacologyInflammatory bowel diseaseIn vivoCarboxylic acidBiochemistryEnzymeImmunologyInternal medicineMedicineGeneBiologyBiotechnologyDiseaseOrganic chemistryHelicobacter pylori-related gastroenterology studiesNF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions