Pyrene-appended bipyridine hydrazone ligand as a turn-on sensor for Cu<sup>2+</sup> and its bioimaging application
Sayed Muktar Hossain, Ved Prakash, Prabhudutta Mamidi, Soma Chattopadhyay, Akhilesh Kumar Singh
Abstract
coordination environment and binding mode, unlike most of the metal sensors due to the lack of a single-crystal structure of the metal sensor complex. Cytotoxicity assay and bioimaging were performed in living cells (Vero cells), giving green fluorescent images. Fluorescence lifetime measurements and theoretical calculations were carried out. The morphology and topographic details on the surface of the metal-organic macrocycle (MOM) were studied by field-emission scanning electron microscopy (FESEM).
Topics & Concepts
ChemistryHydrazoneBipyridineMetal ions in aqueous solutionFluorescenceLigand (biochemistry)Intramolecular forceMetalPyreneIntermolecular forceTitrationCrystallographyCrystal structurePhotochemistryInorganic chemistryStereochemistryMoleculeOrganic chemistryReceptorPhysicsBiochemistryQuantum mechanicsMolecular Sensors and Ion DetectionMetal complexes synthesis and propertiesMetal-Organic Frameworks: Synthesis and Applications