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Clinical trials informed framework for real world clinical implementation and deployment of artificial intelligence applications

Jacqueline Guan-Ting You, Tina Hernandez‐Boussard, Michael A. Pfeffer, Adam Landman, Rebecca G. Mishuris

2025npj Digital Medicine38 citationsDOIOpen Access PDF

Abstract

With rapidly evolving artificial intelligence solutions, healthcare organizations need an implementation roadmap. A "clinical trials" informed approach can promote safe and impactful implementation of artificial intelligence. This framework includes four phases: (1) Safety; (2) Efficacy; (3) Effectiveness and comparison to an existing standard; and (4) Monitoring. Combined with inter-institutional collaboration and national funding support, this approach will advance safe, usable, effective, and equitable deployments of artificial intelligence in healthcare.

Topics & Concepts

Software deploymentClinical trialComputer scienceArtificial intelligenceManagement scienceMedicineSoftware engineeringEngineeringPathologyArtificial Intelligence in Healthcare and EducationArtificial Intelligence in HealthcareMachine Learning in Healthcare