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Successful recovery from COVID‐19 in three kidney transplant recipients who received convalescent plasma therapy

Syed Naeem, Reginald Gohh, George Bayliss, Christopher Cosgrove, Dimitrios Farmakiotis, Basma Merhi, Paul Morrissey, Adena J. Osband, Jeffrey A. Bailey, Joseph Sweeney, Ralph Rogers

2020Transplant Infectious Disease36 citationsDOIOpen Access PDF

Abstract

Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease that typically presents with greater severity in patients with underlying medical conditions or those who are immunosuppressed. We present a novel case series of three kidney transplant recipients with COVID-19 who recovered after receiving COVID-19 convalescent plasma (CCP) therapy. Physicians should be aware of this potentially useful treatment option. Larger clinical registries and randomized clinical trials should be conducted to further explore the clinical and allograft outcomes associated with CCP use in this population.

Topics & Concepts

MedicineConvalescent plasmaCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicineClinical trialKidney transplantationPopulation2019-20 coronavirus outbreakDiseaseInternal medicineInfectious disease (medical specialty)TransplantationVirologyOutbreakEnvironmental healthCOVID-19 Impact on ReproductionCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19