Litcius/Paper detail

3D or not 3D: a guide to assess cell viability in 3D cell systems

Polina Bikmulina, Nastasia V. Kosheleva, Yuri M. Efremov, Artem Antoshin, Zahra Heydari, Валентина Капустина, Valery V. Royuk, Vasily Mikhaylov, В. В. Фомин, Massoud Vosough, Peter Timashev, Yury Rochev, Anastasia Shpichka

2022Soft Matter33 citationsDOI

Abstract

The study aims at revealing the influence of particular 3D cell systems’ parameters such as the components’ concentration, gel thickness, cell density, on the cell viability and applicability of standard assays based on different cell properties.

Topics & Concepts

Viability assayCell survivalCellScaffold3D cell cultureCell biologyChemistryComputational biologyBiochemical engineeringBiologyBiomedical engineeringBiochemistryIn vitroEngineering3D Printing in Biomedical ResearchCellular Mechanics and InteractionsBone Tissue Engineering Materials