Biofilm Formation and Virulence of Shigella flexneri Are Modulated by pH of Gastrointestinal Tract
I-Ling Chiang, Yi Wang, Satoru Fujii, Brian D. Muegge, Qiuhe Lu, Phillip I. Tarr, Thaddeus S. Stappenbeck
Abstract
Shigella infection remains a public health problem in much of the world. Classic models of Shigella pathogenesis suggest that microfold epithelial cells in the small intestine are the preferred initial site of invasion.
Topics & Concepts
Shigella flexneriVirulenceBiologyMicrobiologyShigellaBiofilmGastrointestinal tractBacteriaEscherichia coliSalmonellaBiochemistryGeneticsGeneEscherichia coli research studiesViral gastroenteritis research and epidemiologySalmonella and Campylobacter epidemiology