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Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis

Alexandra V. Bruter, Diana S. Korshunova, Marina V. Kubekina, Петр В. Сергиев, A. A. Kalinina, Leonid A. Ilchuk, Yulia Yu. Silaeva, Eugenii N. Korshunov, Vladislav O. Soldatov, Alexey V. Deykin

2021Transgenic Research17 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTransgeneCre recombinaseGenetically modified mouseGreen fluorescent proteinGene targetingPathogenesisExpression cassetteCoronavirusVirologyCell biologyCoronavirus disease 2019 (COVID-19)Cancer researchVector (molecular biology)ImmunologyDiseaseGeneGeneticsPathologyInfectious disease (medical specialty)Recombinant DNAMedicineSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCRISPR and Genetic Engineering
Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis | Litcius